Resveratrol and Athletic performance

Dr. Auwerx (November 16, 2006) New York Times [28] States that resveratrol converts the structure of muscle to that of a trained athlete without the training.Dr. Auwerx attributes this in large part to the significantly increased number of mitochondria he detected in the muscle cells of treated mice.Mitochondria are the organelles in the body’s cells that generate energy, specifically the energy molecule, adenosine tri-phosphate (ATP). The reseveratrol-fed mice, with extra new mitochondria, were able to burn more fat as a fuel source, thus avoid weight gain, and decreased sensitivity to insulin. This means they tolerated carbohydrates more effectively and had an improved glucose tolerance factor.An ordinary laboratory mouse will run one kilometer on a treadmill before collapsing from exhaustion. However, mice given resveratrol, run twice as far. They also have energy-charged muscles and a reduced heart rate, just as trained athletes do, according to an article published online in CELL by Johan Auwerx and colleagues at the Instituteof Genetics and Molecular and Cellular Biology in Illkirch, France. This is the germinal research addressing the impact of resveratrol in enhancing physical endurance and performance.
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